Chun-Han Chen Selected Research

MPT0L145

12/2021	Combining an Autophagy Inhibitor, MPT0L145, with Abemaciclib Is a New Therapeutic Strategy in GBM Treatment.
9/2019	Targeting Autophagy by MPT0L145, a Highly Potent PIK3C3 Inhibitor, Provides Synergistic Interaction to Targeted or Chemotherapeutic Agents in Cancer Cells.
1/2018	Dual Inhibition of PIK3C3 and FGFR as a New Therapeutic Approach to Treat Bladder Cancer.
5/2016	Trichlorobenzene-substituted azaaryl compounds as novel FGFR inhibitors exhibiting potent antitumor activity in bladder cancer cells in vitro and in vivo.

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Chun-Han Chen Research Topics

Disease

22	Neoplasms (Cancer) 12/2021 - 01/2011
5	Urinary Bladder Neoplasms (Bladder Cancer) 01/2023 - 05/2016
5	Hepatocellular Carcinoma (Hepatoma) 01/2019 - 01/2011
4	Colorectal Neoplasms (Colorectal Cancer) 10/2019 - 04/2011
4	Prostatic Neoplasms (Prostate Cancer) 01/2015 - 01/2011
3	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 10/2023 - 08/2013
2	Neoplasm Metastasis (Metastasis) 12/2023 - 04/2011
2	Retinoblastoma (Glioblastoma, Retinal) 01/2020 - 12/2014
2	Cholangiocarcinoma 02/2017 - 01/2016
2	Infections 01/2017 - 01/2017
2	Body Weight (Weight, Body) 01/2015 - 01/2012
1	Stomach Neoplasms (Stomach Cancer) 12/2023
1	Ischemic Stroke 01/2023
1	Acute Coronary Syndrome 01/2023
1	Hypertension (High Blood Pressure) 01/2023
1	Peripheral Arterial Occlusive Disease 1 01/2023
1	Ependymoma 12/2020
1	Pancreatic Neoplasms (Pancreatic Cancer) 09/2019
1	Gastrointestinal Stromal Tumors (Gastrointestinal Stromal Tumor) 01/2019
1	Malnutrition (Nutritional Deficiencies) 01/2019
1	Liver Cirrhosis (Hepatic Cirrhosis) 01/2018
1	Fatty Liver 01/2018
1	Fibrosis (Cirrhosis) 01/2018
1	Mitochondrial Diseases (Mitochondrial Disease) 01/2018
1	Pneumonia (Pneumonitis) 01/2018
1	Drug Overdose 01/2017
1	Osteoporosis 01/2017
1	Poisoning 01/2017
1	Melanoma (Melanoma, Malignant) 01/2017
1	Cardiovascular Diseases (Cardiovascular Disease) 01/2017
1	Carcinoma (Carcinomatosis) 01/2016
1	Ovarian Neoplasms (Ovarian Cancer) 01/2016
1	B-Cell Lymphoma (Lymphoma, B Cell) 03/2015
1	Inflammation (Inflammations) 01/2015
1	Liver Neoplasms (Liver Cancer) 03/2014

Drug/Important Bio-Agent (IBA)

6	Proteins (Proteins, Gene)FDA Link 01/2020 - 04/2011
6	Histone Deacetylase InhibitorsIBA 11/2015 - 01/2011
5	Histone Deacetylases (Histone Deacetylase)IBA 10/2019 - 01/2011
4	MPT0L145IBA 12/2021 - 05/2016
3	Cisplatin (Platino)FDA LinkGeneric 12/2023 - 01/2016
2	CateninsIBA 12/2023 - 01/2020
2	Tyrosine Kinase InhibitorsIBA 10/2023 - 01/2019
2	abemaciclibIBA 12/2021 - 12/2020
2	B7-H1 AntigenIBA 03/2020 - 10/2019
2	3- (1- benzenesulfonyl- 2,3- dihydro- 1H- indol- 5- yl)- N- hydroxyacrylamideIBA 03/2015 - 03/2014
2	Cadherins (E-Cadherin)IBA 04/2011 - 01/2011
1	Biomarkers (Surrogate Marker)IBA 12/2023
1	Oxaliplatin (Eloxatin)FDA LinkGeneric 12/2023
1	Fluorouracil (Carac)FDA LinkGeneric 12/2023
1	WD repeat containing planar cell polarity effectorIBA 12/2023
1	cucurbitacin EIBA 10/2023
1	stellettin BIBA 01/2023
1	Death-Associated Protein KinasesIBA 01/2023
1	Valsartan (Vals)FDA Link 01/2023
1	Sodium-Glucose Transporter 2 InhibitorsIBA 01/2023
1	entinostat (MS 275)IBA 04/2020
1	ABT751IBA 04/2020
1	Etoposide (VP 16)FDA LinkGeneric 04/2020
1	Vincristine (Oncovin)FDA LinkGeneric 04/2020
1	AfatinibIBA 03/2020
1	compound 17IBA 03/2020
1	Peptide Hydrolases (Proteases)FDA Link 01/2020
1	erdafitinibIBA 01/2020
1	Immune Checkpoint InhibitorsIBA 01/2020
1	pyrimidineIBA 01/2020
1	PF-670462IBA 01/2020
1	Gefitinib (Iressa)FDA Link 09/2019
1	Gemcitabine FDA Link 09/2019
1	Drug CombinationsIBA 09/2019
1	Fibroblast Growth Factor Receptors (Fibroblast Growth Factor Receptor)IBA 09/2019
1	Silybin (Lagosa)IBA 01/2018
1	LipidsIBA 01/2018
1	Pulmonary Surfactants (Pulmonary Surfactant)IBA 01/2018
1	PolymersIBA 01/2017
1	Amitriptyline (Elavil)FDA LinkGeneric 01/2017
1	Matrix Metalloproteinase 9 (Gelatinase B)IBA 01/2017
1	tricarbonyldichlororuthenium (II) dimerIBA 01/2017
1	trichlorobenzeneIBA 05/2016
1	Lovastatin (Mevacor)FDA LinkGeneric 01/2016
1	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 01/2016
1	IntegrinsIBA 01/2016
1	Intercellular Adhesion Molecule-1 (Intercellular Adhesion Molecule 1)IBA 01/2016
1	Antineoplastic Agents (Antineoplastics)IBA 01/2016
1	Lipid NanoparticlesIBA 06/2015
1	AntimetabolitesIBA 06/2015
1	Ribonucleotide Reductases (Ribonucleotide Reductase)IBA 06/2015
1	SilymarinIBA 01/2015
1	SolutionsIBA 01/2015
1	polyethylene glycol 400IBA 01/2015
1	Sorafenib (BAY 43-9006)FDA Link 03/2014
1	Caspase 3 (Caspase-3)IBA 03/2014

Therapy/Procedure

11	Therapeutics 03/2020 - 09/2009
2	Drug Therapy (Chemotherapy) 12/2023 - 01/2016
2	Hepatectomy 01/2019 - 11/2017
2	Gastric Bypass (Roux-en-Y Gastric Bypass) 01/2018 - 01/2015
1	Radiotherapy 12/2023
1	Bariatric Surgery 01/2018
1	Liver Transplantation 02/2017
1	Transplantation 02/2017
1	Contraindications 02/2017